This study examines structures of thinking in social sciences and humanities research, such as the binaries of the biological and/or neurological and the acquired - cultural and/or innate varieties. Such duality became the subject of epistemological inquiry with the consideration of a third factor of natural origin that intervened to create a new social environment, one with an impact going beyond the individual to extend throughout all the relations and contexts of an individual’s existence: Covid-19. Does this influence of viruses extend to the cognitive, behavioural and emotive layers of the human being? Our objective is not to provide definitive answers, but to open the discussion of this new predicament for sciences transformed by new neurological - biological and cultural-viral dimensions.